Review
doi: 10.1016/j.rdc.2006.12.011.
Disease-modifying antirheumatic drug use in the elderly rheumatoid arthritis patient
Affiliations
- PMID: 17367700
- DOI: 10.1016/j.rdc.2006.12.011
Item in Clipboard
Review
Disease-modifying antirheumatic drug use in the elderly rheumatoid arthritis patient
Rheum Dis Clin North Am.
2007 Feb.
Abstract
During the 10-year period since the last review was done by Gardner and Furst, studies have furthered the knowledge of the use of disease-modifying antirheumatic drugs (DMARDs) in the elderly rheumatoid arthritis (RA) patient. This article briefly reviews the clinical pharmacology of humans as they age, and details the effects of aging on the specific pharmacokinetics and responses to commonly used DMARDs. There has been some progress in understanding the elderly RA patient; however, data are insufficient to provide much confidence in DMARDs effects in the elderly.
Similar articles
-
Disease-modifying antirheumatic drug use in the elderly rheumatoid arthritis patient.Clin Geriatr Med. 2005 Aug;21(3):649-69, viii. doi: 10.1016/j.cger.2005.02.010. Clin Geriatr Med. 2005. PMID: 15911212 Review.
-
Disease-modifying antirheumatic drugs.J Hand Surg Am. 2009 Feb;34(2):347-8. doi: 10.1016/j.jhsa.2008.12.008. J Hand Surg Am. 2009. PMID: 19181237 No abstract available.
-
DMARDs in the treatment of rheumatoid arthritis: current agents and future developments.Int J Clin Pract. 2000 May;54(4):243-9. Int J Clin Pract. 2000. PMID: 10912314 Review.
-
Leflunomide for rheumatoid arthritis.Drug Ther Bull. 2000 Jul;38(7):52-4. Drug Ther Bull. 2000. PMID: 11027115 Review.
-
Renal toxicity associated with disease-modifying antirheumatic drugs used for the treatment of rheumatoid arthritis.Semin Arthritis Rheum. 2000 Dec;30(3):196-208. doi: 10.1053/sarh.2000.16641. Semin Arthritis Rheum. 2000. PMID: 11124283 Review.
Cited by
-
Safety and Efficacy of Biological Disease-Modifying Antirheumatic Drugs in Older Rheumatoid Arthritis Patients: Staying the Distance.Drugs Aging. 2016 Jun;33(6):387-98. doi: 10.1007/s40266-016-0374-1. Drugs Aging. 2016. PMID: 27154398 Review.
-
Alopecia areata: a new treatment plan.Clin Cosmet Investig Dermatol. 2011;4:107-15. doi: 10.2147/CCID.S22767. Epub 2011 Jul 22. Clin Cosmet Investig Dermatol. 2011. PMID: 21833161 Free PMC article.
-
Difficult-to-Treat Rheumatoid Arthritis in Older Adults: Implications of Ageing for Managing Patients.Drugs Aging. 2022 Nov;39(11):841-849. doi: 10.1007/s40266-022-00976-5. Epub 2022 Sep 15. Drugs Aging. 2022. PMID: 36104655 Free PMC article.
-
Efficacy of leflunomide for treatment of immune-mediated polyarthritis in dogs: 14 cases (2006-2008).J Am Vet Med Assoc. 2010 Feb 1;236(3):312-8. doi: 10.2460/javma.236.3.312. J Am Vet Med Assoc. 2010. PMID: 20113244 Free PMC article.
-
Pharmacotherapy Pearls in Rheumatology for the Care of Older Adult Patients: Focus on Oral Disease-Modifying Antirheumatic Drugs and the Newest Small Molecule Inhibitors.Rheum Dis Clin North Am. 2018 Aug;44(3):371-391. doi: 10.1016/j.rdc.2018.03.010. Epub 2018 Jun 12. Rheum Dis Clin North Am. 2018. PMID: 30001781 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
