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Case Reports
. 2007 Sep;29(8):522-4.
doi: 10.1016/j.braindev.2007.02.001. Epub 2007 Mar 23.

The evolving MR imaging appearance of lissencephaly: a case report

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Case Reports

The evolving MR imaging appearance of lissencephaly: a case report

Jun-ichi Takanashi et al. Brain Dev. 2007 Sep.

Abstract

MR imaging of a patient with epilepsy and psychomotor retardation at 5 months revealed parieto-occipital pachygyria with almost normal cortical appearance and thickness in the frontal region; this appearance evolved into diffuse pachygyria at 7 years. The change of the MR imaging findings may have resulted from myelination in the intracortical and subcortical fibers. It is important for clinicians to be aware of the longitudinal changes of the cerebral cortex in lissencephaly.

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