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Case Reports
. 2007 May;105(2):545-7.
doi: 10.1016/j.ygyno.2007.01.047. Epub 2007 Mar 21.

A rare gynecological case of paraneoplastic cerebellar degeneration discovered by FDG-PET

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Case Reports

A rare gynecological case of paraneoplastic cerebellar degeneration discovered by FDG-PET

V Marchand et al. Gynecol Oncol. 2007 May.

Abstract

Background: PET/CT may be particularly useful to detect the primary cancer in paraneoplastic cerebellar degeneration (PCD) with anti-Yo which is most commonly associated with breast, ovarian and other gynecological cancers.

Case: A 60-year-old woman developed a PCD associated with anti-Yo antibodies in serum and cerebrospinal fluid. Conventional imaging was negative. FDG-PET showed an abnormal hot spot in the right ovarian area associated with lombo aortic lymph nodes. The diagnosis was confirmed by surgery as an ovarian adenocarcinoma.

Conclusion: In this case report, FDG-PET played a crucial role in detecting the unknown primary tumor in a patient with PCD.

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