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Review
. 2007 Apr;56(4):459-61.
doi: 10.1136/gut.2006.107748.

Transplanting the enteric nervous system: a step closer to treatment for aganglionosis

Affiliations
Review

Transplanting the enteric nervous system: a step closer to treatment for aganglionosis

Michael D Gershon. Gut. 2007 Apr.

Abstract

Autologous transplantation can be used to treat Hirschsprung's disease by implantation and proliferation of the crest‐derived stem cells in vitro

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Conflict of interest statement

Competing interests: None.

Comment on

References

    1. Gariepy C E. Developmental disorders of the enteric nervous system: genetic and molecular bases. J Pediatr Gastroenterol Nutr 2004395–11. - PubMed
    1. Parisi M A, Kapur R P. Genetics of Hirschsprung disease. Curr Opin Pediatr 200012610–617. - PubMed
    1. Newgreen D, Young H M. Enteric nervous system: development and developmental disturbances—part 1. Pediatr Dev Pathol 20025224–247. - PubMed
    1. McCallion A S, Stames E, Conlon R A.et al Phenotype variation in two‐locus mouse models of Hirschsprung disease: tissue‐specific interaction between Ret and Ednrb. Proc Natl Acad Sci USA 20031001826–1831. - PMC - PubMed
    1. Lang D, Chen F, Milewski R.et al Pax3 is required for enteric ganglia formation and functions with Sox10 to modulate expression of c‐ret. J Clin Invest 2000106963–971. - PMC - PubMed

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