Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2007 Jan;13(1):147-9.
doi: 10.3201/eid1301.060617.

Reemergence of endemic Chikungunya, Malaysia

Affiliations

Reemergence of endemic Chikungunya, Malaysia

Sazaly AbuBakar et al. Emerg Infect Dis. 2007 Jan.

Abstract

Chikungunya virus infection recently reemerged in Malaysia after 7 years of nondetection. Genomic sequences of recovered isolates were highly similar to those of Malaysian isolates from the 1998 outbreak. The reemergence of the infection is not part of the epidemics in other Indian Ocean countries but raises the possibility that chikungunya virus is endemic in Malaysia.

PubMed Disclaimer

Figures

Figure
Figure
Phylogenetic relationships of chikungunya virus isolates from the Malaysia 2006 outbreak. The neighbor-joining tree was constructed using nucleic acid sequences of the envelope glycoprotein E1 gene, with O’nyong nyong virus (GenBank accession no. NC_001512) as the outgroup virus. * indicates isolates from the Malaysia 2006 outbreak; † indicates Australia SM287. Bootstrap values are shown as percentages derived from 1,000 samplings. The scale reflects the number of nucleotide substitutions per site along the branches.

References

    1. Lam SK, Chua KB, Hooi PS, Rahimah MA, Kumari S, Tharmaratnam M, et al. Chikungunya infection - an emerging disease in Malaysia. Southeast Asian J Trop Med Public Health. 2001;32:447–51. - PubMed
    1. Paganin F, Borgherini G, Staikowsky F, Arvin-Berod C, Poubeau P. Chikungunya on Réunion Island: chronicle of an epidemic foretold. Presse Med. 2006;35:641–6. 10.1016/S0755-4982(06)74657-7 - DOI - PubMed
    1. Harnett GB, Bucens MR. Isolation of chikungunya virus in Australia. Med J Aust. 1990;152:328–9. - PubMed
    1. Hasebe F, Parquet MC, Pandey BD, Mathenge EG, Morita K, Balasubramaniam V, et al. Combined detection and genotyping of chikungunya virus by a specific reverse transcription-polymerase chain reaction. J Med Virol. 2002;67:370–4. 10.1002/jmv.10085 - DOI - PubMed
    1. Pfeffer M, Linssen B, Parke MD, Kinney RM. Specific detection of chikungunya virus using a RT-PCR/nested PCR combination. J Vet Med B Infect Dis Vet Public Health. 2002;49:49–54. 10.1046/j.1439-0450.2002.00535.x - DOI - PubMed

LinkOut - more resources