Review
doi: 10.1038/sj.icb.7100050.
Epub 2007 Mar 20.
Quantifying HTLV-I dynamics
Affiliations
- PMID: 17372609
- DOI: 10.1038/sj.icb.7100050
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Review
Quantifying HTLV-I dynamics
Immunol Cell Biol.
2007 Jun.
Abstract
Despite significant advances in our understanding of the immune response to persistent viruses like human T-cell lymphotropic virus type I (HTLV-I), many important questions remain unanswered. Mathematical modelling enables us to interpret and synthesise diverse experimental data in new ways and thus can contribute to our understanding. Here, we review recent advances in mathematical modelling of HTLV-I infection and illustrate how mathematics has enabled us to identify factors that determine an individual's viral burden and risk of developing HTLV-I-associated diseases.
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