Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2007 Mar 20:3:4.
doi: 10.1186/1745-9974-3-4.

Defining the relationship between gastroesophageal reflux and cough: probabilities, possibilities and limitations

Matthew M Eastburn  1 , Peter H Katelaris, Anne B Chang
Affiliations

Defining the relationship between gastroesophageal reflux and cough: probabilities, possibilities and limitations

Matthew M Eastburn et al. Cough. .

Abstract

The common co-existence of cough and gastroesophageal reflux disease (GORD) is well established. However, ascertaining cause and effect is more difficult for many reasons that include occurrence by chance of two common symptoms, the changing definition of GORD, equipment limitations and the lack of randomised controlled trials. Given these difficulties, it is not surprising that there is disparity of opinion between respiratory and gastroenterology society guidelines on the link between GORD and chronic cough. This commentary explores of these issues.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Cough preceding a pH drop followed by another cough. Recordings from a specifically built pHmetry-cough-logger with a capture rate of 10 Hz (40 times the commercially available systems). Time scale in hours:mins:secs.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Irwin RS, Boulet LP, Cloutier MM, Fuller R, Gold PM, Hoffstein V, Ing AJ, McCool FD, O'Byrne P, Poe RH, Prakash UB, Pratter MR, Rubin BK. Managing cough as a defense mechanism and as a symptom. A consensus panel report of the American College of Chest Physicians. Chest. 1998;114:133S–181S. - PubMed
    1. Irwin RS, Baumann MH, Bolser DC, Boulet LP, Braman SS, Brightling CE, Brown KK, Canning BJ, Chang AB, Dicpinigaitis PV, Eccles R, Glomb WB, Goldstein LB, Graham LM, Hargreave FE, Kvale PA, Lewis S, McCool FD, McCrory DC, Prakash UB, Pratter MR, Rosen MJ, Schulman E, Shannon JJ, Smith Hammond C, Tarlo SM. Diagnosis and Management of Cough Executive Summary: ACCP Evidence-Based Clinical Practice Guidelines. Chest. 2006;129:1S–23. doi: 10.1378/chest.129.1_suppl.1S. - DOI - PMC - PubMed
    1. Morice AH, members C. The diagnosis and management of chronic cough. Eur Respir J. 2004;24:481–492. doi: 10.1183/09031936.04.00027804. - DOI - PubMed
    1. Kohno S, Ishida T, Uchida Y, Kishimoto H, Sasaki H, Shioya T, Tokuyama K, Niimi A, Nishi K, Fujimura M, Matsuse H, Suzaki H. The Japanese Respiratory Society guidelines for management of cough. Respirology. 2006;11 Suppl 4:S135–S186. - PubMed
    1. Morice AH, McGarvey L, Pavord I. Recommendations for the management of cough in adults. Thorax. 2006;61 Suppl 1:i1–i24. doi: 10.1136/thx.2006.065144. - DOI - PMC - PubMed

LinkOut - more resources