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Review
. 2007 Mar;26(3):275-7.
doi: 10.1016/j.immuni.2007.03.003.

Aiolos: an ungrateful member of the Ikaros family

Dimitris Kioussis  1
Affiliations
Review

Aiolos: an ungrateful member of the Ikaros family

Dimitris Kioussis. Immunity. 2007 Mar.

Abstract

Ikaros family members play an important role in hematopoietic development. Thompson et al. (2007) show that pre-BCR signaling induces Aiolos expression, which in turn suppresses the expression of the pre-BCR component lambda5 and eliminates the very structure that signaled its appearance.

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