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. 2007 Feb;9(1):46-51.
doi: 10.1007/s11936-007-0050-1.

Lipid-independent pleiotropic effects of statins in the management of acute coronary syndromes

Kausik K Ray  1 , Christopher P Cannon
Affiliations

Lipid-independent pleiotropic effects of statins in the management of acute coronary syndromes

Kausik K Ray et al. Curr Treat Options Cardiovasc Med. 2007 Feb.

Abstract

Acute coronary syndromes involve a complex interplay between the vessel wall, inflammatory cells, and the coagulation cascade. Statins possess beneficial effects that are independent of low-density lipoprotein cholesterol lowering and that have favorable effects on inflammation, the endothelium, and the coagulation cascade. There is now accumulating evidence that these lipid-independent pleiotropic effects are clinically relevant in the management of acute coronary syndromes.

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