[Diagnosis and treatment of chronic venous ulcer: research status and new strategies]

Abstract

The persistent venous hypertension is the primary cause of venous ulcer, and leukocyte activation plays an important role in the formation of venous ulcer. Venous ulcer should be differentiated from ulcers resulted from other diseases. Treatment options include conservative/medical therapies and surgical therapies. Injection sclerotherapy, superficial vein ligation and stripping, deep vein valve reconstruction, perforator ligation, and skin grafting favor the healing of ulcers.