Pulmonary venous flow assessed by Doppler echocardiography in the management of atrial fibrillation

Abstract

Pulmonary venous blood flow (PVF) visualized by Doppler echocardiography exhibits a pulsatile behavior, which is related to left atrial pressure and function, mitral valve function, and left ventricular compliance. In atrial fibrillation (AF), the disappearance of atrial reverse flow, a decrease in systolic flow with a greater diastolic than systolic flow, a prolonged onset of systolic flow and the appearance of an early systolic reverse flow are characteristic findings. A reduction in systolic PVF expressed by reduced peak velocity, reduced velocity-time integral of systolic flow, and reduced systolic fraction of PVF has been found to be associated with reduced left atrial appendage flow, left atrial spontaneous echo contrast formation, frequency of AF paroxysms and propensity for AF recurrence following restoration of sinus rhythm. Ablation techniques targeting pulmonary vein ostia and adjacent left atrium are promising treatment options to cure AF. Monitoring the PVF response to and adjusting of ablation procedures has been suggested to optimize outcome and prevent complications such as pulmonary vein stenosis. In conclusion, assessment of PVF variables and patterns by Doppler echocardiography seems useful in the management of AF patients. Especially the reduction in systolic PVF may be used as marker for left atrial dysfunction which favors thrombus formation and AF reinitiation. Finally, PVF monitoring has the potential to an increasing role in AF ablation procedures.