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. 1992 Mar;66(3):1389-93.
doi: 10.1128/JVI.66.3.1389-1393.1992.

LRV1 viral particles in Leishmania guyanensis contain double-stranded or single-stranded RNA

R Weeks  1 , R F Aline Jr, P J Myler, K Stuart
Affiliations

LRV1 viral particles in Leishmania guyanensis contain double-stranded or single-stranded RNA

R Weeks et al. J Virol. 1992 Mar.

Abstract

The 32-nm-diameter spherical viral particles found in the cytoplasm of Leishmania guyanensis CUMC1-1A sediment at 130S and have a buoyant density of approximately 1.4 g/ml in cesium chloride gradients. These particles contain a 5.3-kb double-stranded RNA, while single-stranded RNA that corresponds to the viral positive strand is associated with less-dense particles. These results suggest a conservative and sequential mode of LRV1 viral RNA replication that is exemplified by the ScV L-A virus of yeast.

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