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Review
. 2007 Mar;11(1):18-25.
doi: 10.1007/s10157-006-0448-1. Epub 2007 Mar 28.

Endothelial progenitor cells for postnatal vasculogenesis

Masamichi Eguchi  1 , Haruchika Masuda, Takayuki Asahara
Affiliations
Review

Endothelial progenitor cells for postnatal vasculogenesis

Masamichi Eguchi et al. Clin Exp Nephrol. 2007 Mar.

Abstract

Bone marrow-derived endothelial progenitor cells (EPCs) are present in the systemic circulation, are augmented in response to certain cytokines and/or tissue ischemia, and are home to--as well as incorporate into--sites of neovascularization. On the basis of these aspects, EPCs have attractive potential therapeutic applications for cardiovascular ischemic diseases as a novel cell-based strategy, mainly via a vasculogenesis mechanism. This review provides an update of the biology of EPCs, as well as highlighting the potential use of these cells for therapeutic regeneration.

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