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Review
. 2007 Mar;30(3):110-5.
doi: 10.1002/clc.20034.

Left bundle-branch block--pathophysiology, prognosis, and clinical management

Pietro Francia  1 , Cristina Balla, Francesco Paneni, Massimo Volpe
Affiliations
Review

Left bundle-branch block--pathophysiology, prognosis, and clinical management

Pietro Francia et al. Clin Cardiol. 2007 Mar.

Abstract

Given its broad use as a screening tool, the electrocardiogram (ECG) has largely become one of the most common diagnostic tests performed in routine clinical practice. As a result, the finding of left bundle-branch block (LBBB) in the absence of a well-defined clinical setting has become relatively frequent and raises questions and often concerns. While in the absence of clinically detectable heart disease LBBB does not necessarily imply poor outcomes, physicians should be aware of the role of LBBB in stratifying risk of cardiovascular events and death in subjects with both ischemic and nonischemic heart disease. This paper reviews historical landmarks, pathophysiologic features, prognostic implications, and clinical management of LBBB in apparently healthy subjects and those with heart disease.

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References

    1. Eppinger H, Rothberger CJ. Zur Analyse des Elektrokardiogramms. Wien Klin Wochenschr 1909;22:1091–1098.
    1. Eppinger H, Rothberger J: Uber die Folgen der Durchschneidung der tawaraschen schenkel des Reizleitungssystems. Klin Med 1910;70:1–20.
    1. Eppinger H, Stoerk O: Zur Klinik des Elektrokardiogramms. Klin Med 1910;71:157–164.
    1. Massing GK, James TN: Anatomical configuration of the His bundle and bundle branches in the human heart. Circulation 1976;53:609–621. - PubMed
    1. Lev M, Bharati S: Anatomic basis for impulse generation and atrioventricular transmission In His‐Bundle Electrocardiography and Clinical Electrophysiology (Ed. Narula OS). Philadelphia: FA Davis, 1976:I.