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Comment
. 2007 Apr;71(7):604-5.
doi: 10.1038/sj.ki.5002121.

Renal ischemia-reperfusion injury: renal dendritic cells loudly sound the alarm

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Comment

Renal ischemia-reperfusion injury: renal dendritic cells loudly sound the alarm

P J Nelson. Kidney Int. 2007 Apr.
Free article

Abstract

Renal ischemia-reperfusion injury is a major cause of acute renal failure and kidney allograft dysfunction. Dong and colleagues now identify the surveying renal dendritic cell network as the predominant source of tumor necrosis factor-alpha during the early stages of renal ischemia-reperfusion injury, raising the possibility for direct targeting of renal dendritic cells to help ameliorate this common form of renal injury and its sequelae.

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