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. 2008 Jun;35(2):189-93.
doi: 10.1007/s11033-007-9069-3. Epub 2007 Mar 27.

Transcriptional inhibition by a non-histone protein from low mobility group in homologous and heterologous in vitro systems

Maryam Shahhoseini  1 , Azra Rabbani-Chadegani
Affiliations

Transcriptional inhibition by a non-histone protein from low mobility group in homologous and heterologous in vitro systems

Maryam Shahhoseini et al. Mol Biol Rep. 2008 Jun.

Abstract

An acidic non-histone chromosomal protein of low mobility group (LMG) with pI of 5-5.5 and molecular weight of 160 kDa (named LMG160), has been isolated from rat liver nuclei and its inhibitory effect on transcription of DNA in vitro has been detected in a heterologous prokaryotic in vitro transcription system (T7 RNA polymerase) and also confirmed in the homologous cell-free system of rat liver nuclear extract. The results indicate that in the presence of non-histone protein LMG160, in vitro RNA synthesis represses in the both systems, which can suggest a functional role for this non-histone chromosomal protein.

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References

    1. Nature. 1970 Aug 15;227(5259):680-5 - PubMed
    1. Eur J Biochem. 1973 Dec 3;40(1):215-9 - PubMed
    1. Nucleic Acids Res. 2001 Mar 1;29(5):1047-53 - PubMed
    1. Mol Cell Biol. 1999 Aug;19(8):5237-46 - PubMed
    1. Biochem Biophys Res Commun. 1990 Jan 15;166(1):11-21 - PubMed

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