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. 2007 Jan;60(1):36-42.
doi: 10.1038/ja.2007.5.

Bromoalterochromides A and A', unprecedented chromopeptides from a marine Pseudoalteromonas maricaloris strain KMM 636T

Michael Speitling  1 , Olga F Smetanina, Tatyana A Kuznetsova, Hartmut Laatsch
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Bromoalterochromides A and A', unprecedented chromopeptides from a marine Pseudoalteromonas maricaloris strain KMM 636T

Michael Speitling et al. J Antibiot (Tokyo). 2007 Jan.

Abstract

The marine strain Pseudoalteromonas maricaloris KMM 636T was found to produce an inseparable mixture of two brominated yellow main pigments, bromoalterochromide A and A', in a ratio of 3: 1. Both pigments are Thr-Val-Asn-Asn-X pentapeptide lactones, where the amino group of Thr is acylated with 9-(3-bromo-4-hydroxyphenyl)-nona-2,4,6,8-tetraenoic acid, and X is aIle and Leu, respectively. They possess cytotoxic effects on developing eggs of the sea urchin Strongylocentrotus intermedius, but no antibiotic activity.

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