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Case Reports
. 2007 Jul 15;258(1-2):148-50.
doi: 10.1016/j.jns.2007.02.029. Epub 2007 Mar 27.

Fisher/Gullain-Barré overlap syndrome in advanced AIDS

Akiyuki Hiraga  1 , Satoshi Kuwabara, Akira Nakamura, Nobuhiro Yuki, Takamichi Hattori, Takashi Matsunaga
Affiliations
Case Reports

Fisher/Gullain-Barré overlap syndrome in advanced AIDS

Akiyuki Hiraga et al. J Neurol Sci. .

Abstract

Human immunodeficiency virus-associated Guillain-Barré syndrome typically occurs early in HIV infection before AIDS develops. We report a 56-year-old male AIDS patient, who developed overlapping Fisher/Guillain-Barré syndrome despite markedly decreased CD4 cell counts. Serum anti-GQ1b IgG antibody was positive. His condition improved rapidly after immunoglobulin treatment. This indicates that Fisher/Guillain-Barré syndrome may occur even in severely immunosuppressed patients and that anti-ganglioside antibody production is possibly mediated by a T cell-independent process.

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