Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2007 Feb 21:(7):728-30.
doi: 10.1039/b617260a. Epub 2007 Jan 18.

Stereospecific construction of substituted piperidines. Synthesis of (-)-paroxetine and (+)-laccarin

John F Bower  1 , Thomas Riis-Johannessen, Peter Szeto, Andrew J Whitehead, Timothy Gallagher
Affiliations

Stereospecific construction of substituted piperidines. Synthesis of (-)-paroxetine and (+)-laccarin

John F Bower et al. Chem Commun (Camb). .

Abstract

Short and efficient enantioselective syntheses of (-)-paroxetine and (+)-laccarin are described based on the highly stereospecific cleavage of C(3)-substituted 1,3-cyclic sulfamidates.

PubMed Disclaimer

Publication types

MeSH terms