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Randomized Controlled Trial
. 2007 Mar;27(1):3-6.

Thirty cases of obsession treated by point-stimulation and with small dose of chlorimipramine

Bin Feng  1 , Lanying Liu, Xu Fangzhong, Jiong Chen, Peirong Wang, Wensong Chen, Enyan Yu
Affiliations
  • PMID: 17393613
Randomized Controlled Trial

Thirty cases of obsession treated by point-stimulation and with small dose of chlorimipramine

Bin Feng et al. J Tradit Chin Med. 2007 Mar.

Abstract

Objective: To investigate the clinical therapeutic effects of point-stimulation for obsession.

Methods: Sixty cases of obsession were divided into two groups: a control group of 30 cases treated with chlorimipramine (Chl), and a treatment group of 30 cases treated by point-stimulation (PS) plus chlorimipramine (PS+Chl). The therapeutic effects and side-effect were evaluated according tb the criteria set in Yale-Brown Obsession Scale (Y-BOCS), Hamilton's depression scale (HAMD), brief psychiatric rating scale (BPRS) and treatment emergent symptom scale (TESS).

Results: The cure rate and markedly effective rate were respectively 26.7% and 56.6% in the control group, and 43.3% and 50% in the treatment group, suggesting that the therapeutic effect in the treatment group was better than that in the control group. The incidence of adverse side-effects was 73.33% in the control group and 46.67% in the treatment group, with a significant difference between the two groups (P<0.05).

Conclusion: Point-stimulation plus small dose of chlorimipramine was superior to the simple chlorimipramine treatment, indicating that the combined method was more effective and safe for obsession with less side effects.

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