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Review
. 2007;8(3):208.
doi: 10.1186/gb-2007-8-3-208.

Hox go omics: insights from Drosophila into Hox gene targets

Anastasios Pavlopoulos  1 , Michael Akam
Affiliations
Review

Hox go omics: insights from Drosophila into Hox gene targets

Anastasios Pavlopoulos et al. Genome Biol. 2007.

Abstract

Genetic studies of the targets of the Hox genes have revealed only the tip of the iceberg. Recent microarray studies that have identified hundreds more transcriptional responses to Hox genes in Drosophila will help elucidate the role of Hox genes in development and evolution.

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Figures

Figure 1
Figure 1
Microarray expression profiling for identification of Hox downstream targets. (a) Hueber et al. [8] compared Drosophila embryos overexpressing a control lacZ gene (blue) with embryos individually overexpressing various Hox genes (yellow). (b) Hersh et al. [9] searched for targets of Ultrabithorax (green) in haltere imaginal discs by comparing their transcriptome with that of wing imaginal discs (gray).
See this image and copyright information in PMC

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