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Clinical Trial
. 1992 Mar;57(3):559-64.
doi: 10.1016/s0015-0282(16)54900-0.

Intrauterine insemination outperforms intracervical insemination in a randomized, controlled study with frozen, donor semen

P E Patton  1 , K A Burry, A Thurmond, M J Novy, D P Wolf
Affiliations
Free article
Clinical Trial

Intrauterine insemination outperforms intracervical insemination in a randomized, controlled study with frozen, donor semen

P E Patton et al. Fertil Steril. 1992 Mar.
Free article

Abstract

Objective: To assess the efficacy of intrauterine insemination (IUI) in a donor insemination program.

Design: Prospective randomized clinical trial.

Setting: Donor insemination program.

Patients, participants: Women undergoing insemination were randomly assigned to receive either IUI or intracervical insemination for a maximum of six cycles.

Interventions: None.

Main outcome measure(s): Cycle fecundity rates between the two routes were compared.

Results: The monthly fecundity rate for intracervical insemination was 5.1% compared with 23% by IUI. By life table analysis, pregnancy rates for IUI were significantly higher than intracervical insemination (P = 0.02).

Conclusions: Intrauterine insemination with quarantined donor sperm is superior to intracervical insemination.

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