Gliosarcoma with infratemporal fossa extension. Case report
- PMID: 17405263
- DOI: 10.3171/jns.2006.105.6.904
Gliosarcoma with infratemporal fossa extension. Case report
Abstract
Gliosarcomas are bimorphic intraaxial tumors. Involvement of the skull base is highly unexpected. The authors present the case of a temporal lobe gliosarcoma with significant infratemporal fossa extension. This 55-year-old man presented with a 1-month history of severe progressive headache. Neurological examination was unremarkable except for bilateral papilledema. Magnetic resonance imaging revealed a 6-cm right temporal mass with extension into the infratemporal fossa. The patient underwent a right frontotemporal craniotomy together with drilling of the sphenoid ridge and middle fossa floor. The tumor consisted of intraaxial, intracranial as well as extradural, and extracranial components with extension to the posterolateral wall of the sphenoid sinus. It had a relatively well-circumscribed dissection plane. Gross-total resection was achieved, and the middle fossa floor was reconstructed using a rotated temporalis muscle flap. The postoperative course was uneventful except for hypesthesia in the distribution of the maxillary division of the right trigeminal nerve. The histopathological diagnosis was consistent with gliosarcoma. Radiotherapy and chemotherapy consisting of temozolomide were administered subsequently, and the patient was recurrence free 12 months after his initial diagnosis. In the presence of a mass lesion with both intraaxial and extracranial involvement, gliosarcoma should be considered among the differential diagnoses. Aggressive resection should be attempted, including the use of skull base surgical techniques to ensure an optimal outcome. The effect of skull base involvement to the overall treatment and outcome of patients with gliosarcomas would be difficult to determine given the rare occurrence of these lesions in such locations.
Similar articles
-
Bilateral eyebrow incision, mini-supraorbital craniotomy with extended frontobasal approach for extensive anterior and middle cranial fossa skull base tumors.Acta Neurochir (Wien). 2011 Mar;153(3):527-31. doi: 10.1007/s00701-010-0888-y. Epub 2010 Dec 15. Acta Neurochir (Wien). 2011. PMID: 21161297 No abstract available.
-
Recurrent intracranial esthesioneuroblastoma outside the initial field of radiation with progressive dural and intra-orbital invasion.Acta Neurochir (Wien). 2004 Feb;146(2):179-82. doi: 10.1007/s00701-003-0179-y. Epub 2003 Dec 22. Acta Neurochir (Wien). 2004. PMID: 14963753
-
Ameloblastic fibrosarcoma involving the anterior and middle skull base with intradural extension.J Craniofac Surg. 2009 Nov;20(6):2087-90. doi: 10.1097/SCS.0b013e3181c50cf7. J Craniofac Surg. 2009. PMID: 19884826 Review.
-
Dumbbell-shaped middle cranial fossa meningioma with interdural cavernous sinus extension: report of two cases with complete removal.Surg Neurol. 2006 Sep;66(3):315-9; discussion 319-20. doi: 10.1016/j.surneu.2005.11.060. Surg Neurol. 2006. PMID: 16935645
-
Fronto-orbito-zygomatic (FOZ) approach for infratemporal fossa lesions extending to middle cranial fossa: our experience and review of literature.Neurol Neurochir Pol. 2022;56(2):178-186. doi: 10.5603/PJNNS.a2022.0023. Epub 2022 Mar 18. Neurol Neurochir Pol. 2022. PMID: 35302232 Review.
Cited by
-
Multidisciplinary approaches to gliosarcoma: A case report and review of the literature.Clin Case Rep. 2022 Aug 23;10(8):e5985. doi: 10.1002/ccr3.5985. eCollection 2022 Aug. Clin Case Rep. 2022. PMID: 36017117 Free PMC article.
-
Honokiol crosses BBB and BCSFB, and inhibits brain tumor growth in rat 9L intracerebral gliosarcoma model and human U251 xenograft glioma model.PLoS One. 2011 Apr 29;6(4):e18490. doi: 10.1371/journal.pone.0018490. PLoS One. 2011. PMID: 21559510 Free PMC article.
-
Post-Treatment Gliosarcoma Extension into the Pterygomaxillary Fossa: Literature Review and Case Report.Cureus. 2016 Jul 18;8(7):e700. doi: 10.7759/cureus.700. Cureus. 2016. PMID: 27699141 Free PMC article. Review.
-
Gliosarcoma with Primary Skull Base Invasion.Case Rep Radiol. 2016;2016:1762195. doi: 10.1155/2016/1762195. Epub 2016 Dec 8. Case Rep Radiol. 2016. PMID: 28053799 Free PMC article.
-
Gliosarcoma with bone infiltration and extracranial growth: case report and review of literature.J Neurooncol. 2011 Jul;103(3):765-70. doi: 10.1007/s11060-010-0437-9. Epub 2010 Oct 19. J Neurooncol. 2011. PMID: 20957407 Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources