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. 1992 Jan;18(1):17-21.
doi: 10.1111/j.1524-4725.1992.tb03295.x.

Treatment of glabellar frown lines with C. botulinum-A exotoxin

J D Carruthers  1 , J A Carruthers
Affiliations

Treatment of glabellar frown lines with C. botulinum-A exotoxin

J D Carruthers et al. J Dermatol Surg Oncol. 1992 Jan.

Abstract

Eighteen patients with glabellar frown lines were treated with C. botulinum-A exotoxin. Sixteen of the 17 patients followed showed improvement for periods ranging from 3 months to 11 months. Side-effects were minimal and transient. Because C. botulinum-A exotoxin therapy of glabellar frown lines treats the underlying cause of these lines, it is more effective than soft tissue augmentation although this improvement is temporary. Treatment with C. botulinum-A exotoxin is a simple, safe procedure.

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