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. 2007;23(5-6):448-52.
doi: 10.1159/000101470. Epub 2007 Apr 2.

Fibromuscular dysplasia may herald symptomatic recurrence of cervical artery dissection

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Fibromuscular dysplasia may herald symptomatic recurrence of cervical artery dissection

J M de Bray et al. Cerebrovasc Dis. 2007.

Abstract

Background: The prevalence of fibromuscular dysplasia (FMD) in patients with cervical artery dissection (CAD) is unknown. Our objectives were to assess the risk of CAD recurring as a stroke or a transient ischemic attack and the association of these events with FMD.

Methods: We prospectively included and followed 103 consecutive patients who had been admitted for a CAD. The median follow-up was 4 years (range 4 months to 10 years). The main criteria for inclusion were a mural hematoma demonstrated by cervical magnetic resonance imaging and/or signs suggesting CAD on 2 other investigations. FMD was diagnosed on the so-called string of beads pattern by digital subtraction angiography.

Results: Five patients had CAD recurrence (60% occurred late). Four of these 5 patients had FMD. In 4 patients, CAD recurrence involved another cervical artery.

Conclusion: The rate of symptomatic CAD recurrence was 1% per year and was often related to FMD.

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