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. 2007 Apr 21:(15):1556-8.
doi: 10.1039/b617871e. Epub 2007 Feb 5.

Phosphine containing oligonucleotides for the development of metallodeoxyribozymes

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Phosphine containing oligonucleotides for the development of metallodeoxyribozymes

Loïc Ropartz et al. Chem Commun (Camb). .

Abstract

Novel transition metal catalysts based on oligonucleotides can be easily obtained by functionalization of 5-iodouridine with phosphine ligands, resulting in good asymmetric induction in palladium catalyzed allylic nucleophilic substitution.

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