Phosphine containing oligonucleotides for the development of metallodeoxyribozymes
- PMID: 17406706
- DOI: 10.1039/b617871e
Phosphine containing oligonucleotides for the development of metallodeoxyribozymes
Abstract
Novel transition metal catalysts based on oligonucleotides can be easily obtained by functionalization of 5-iodouridine with phosphine ligands, resulting in good asymmetric induction in palladium catalyzed allylic nucleophilic substitution.
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