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. 2007;120(5):773-8.
doi: 10.1016/j.thromres.2006.12.018. Epub 2007 Apr 3.

Enhanced fibrinolysis in fingerstick blood samples: a possible role for matrix metalloproteinase-9

Rachna Vanjani  1 , Melissa Park, Brittany Holt, Ann Cullinane, Paula Merryman, McDonald Horne
Affiliations

Enhanced fibrinolysis in fingerstick blood samples: a possible role for matrix metalloproteinase-9

Rachna Vanjani et al. Thromb Res. 2007.
No abstract available

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Figures

Figure 1
Figure 1
Log FDP concentration (log μg/mL) in fingerstick (small open circles) and venipuncture (small closed circles) serum after 1 hour, 24 hours, and 48 hours incubation at 37°. Lines connect the means (large circles) of the data points. P-values for the differences in the means of the fingerstick and venipuncture results are indicated for the three time intervals.
Figure 2
Figure 2
Log MMP-3 concentration (log ng/mL) in fingerstick (small open circles) and venipuncture (small closed circles) serum after 1 hour, 24 hours, and 48 hours incubation at 37°. Lines connect the means (large circles) of the data points.
Figure 3
Figure 3
Log proMMP-9 concentration (log ng/mL) in fingerstick (small open circles) and venipuncture (small closed circles) serum after 1 hour, 24 hours, and 48 hours incubation at 37°. Lines connect the means (large circles) of the data points. P-values (based upon paired t-tests) for the differences in the means of the fingerstick and venipuncture results are indicated for the three time intervals.
Figure 4
Figure 4
Log neutrophil elastase concentration (log ng/mL) in fingerstick (open circles) and venipuncture (closed circles) serum from a single subject after 1 hour, 24 hours, and 48 hours incubation at 37°.
Figure 5
Figure 5
Log FDP concentration (log μg/mL) in venipuncture serum after 1 hour, 24 hours, and 48 hours incubation at 37° in control samples (small open circles) or samples containing ~ 3.5 μg/mL MMP-9 catalytic domain (small closed circles). Lines connect the means (large circles) of the data points. P-values (based upon paired –tests) for the differences in the means of the results with or without MMP-9 catalytic domain are indicated for the three time intervals.
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References

    1. Cesarman-Maus G, Hajjar KA. Molecular mechanisms of fibrinolysis. Br J Haematol. 2005;129:307–21. - PubMed
    1. Nagase H, Woessner JF. Matrix metalloproteinases. J Biol Chem. 1999;274:21491–4. - PubMed
    1. Lijnen HR. Matrix metalloproteinases and cellular fibrinolytic activity. Biochemistry (Moscow) 2002;67:107–15. - PubMed
    1. Horne MK, Merryman PK, Cullinane AM. Plasminogen interaction with platelets: the importance of carboxyterminal lysines. Thromb Res. 2005;116:499–507. - PubMed
    1. Horne M, Merryman P, Cullinane A, Hutchison K. Fibrinolysis in clots of blood obtained by fingerstick. Blood. 1997;90(suppl 1):96b.

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