Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1975 Dec;72(12):4991-3.
doi: 10.1073/pnas.72.12.4991.

Signal input for a chemotactic response in the cellular slime mold Dictyostelium discoideum

J M Mato, A Losada, V Nanjundiah, T M Konijn

Signal input for a chemotactic response in the cellular slime mold Dictyostelium discoideum

J M Mato et al. Proc Natl Acad Sci U S A. 1975 Dec.

Abstract

Drops with different concentrations of 3':5'-cyclic AMP were deposited at various distances from small populations of Dictyostelium discoideum amoebae, and the distances over which 50% of the amoebae drops reacted positively were determined. The linear regression analysis of a bouble logarithmic plot of distance against concentration gives a straight line with a slope of 1/4.25, which value suggests that the amoebae respond to a spatial gradient of cyclic AMP concentration. The threshold value for the signal is 3.6 X 10(-9) M/mm with a sensitivity of measurement of about 1%. These findings are discussed in relation to our present knowledge of cyclic AMP receptors.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Dev Biol. 1961 Dec;3:725-56 - PubMed
    1. Biochim Biophys Acta. 1975 Apr 7;385(2):173-9 - PubMed
    1. Experientia. 1970 Apr 15;26(4):367-9 - PubMed
    1. Nature. 1974 May 31;249(456):450-2 - PubMed
    1. Proc Natl Acad Sci U S A. 1974 Jun;71(6):2423-7 - PubMed

LinkOut - more resources