Orbital metastasis as a rare form of clinical presentation of non-small cell lung cancer

Abstract

Approximately 11 million new cases of cancer are diagnosed worldwide each year; one in eight is a lung cancer. More than one million people die of lung cancer each year, and non-small cell lung cancer accounts for approximately 80% of all cases of lung cancer. The incidence of primary tumors that metastasize to the orbit is approximately 7%. In 19% of the cases, there is no history of cancer when the patient presents with ophthalmic symptoms, and in 10%, the primary site remains obscure despite intensive systemic evaluation. We report a rare form of clinical presentation of non-small cell lung cancer in which symptoms caused by orbital metastases were the first manifestations.