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. 1976 Feb;73(2):327-30.
doi: 10.1073/pnas.73.2.327.

5'-terminal structure of poliovirus polyribosomal RNA is pUp

M J Hewlett, J K Rose, D Baltimore

5'-terminal structure of poliovirus polyribosomal RNA is pUp

M J Hewlett et al. Proc Natl Acad Sci U S A. 1976 Feb.

Abstract

Poliovirus RNA purified from virus-specific polyribosomes does not contain m7G in a 5'-5'-pyrophosphate linkage at its 5'-end. The only potential 5'-end found in ribonuclease digests of this RNA is pUp, which is present in a yield of 1 mole/mole of poliovirus RNA. We conclude that a 5'-terminal m7G is not required for translation of at least one RNA species in animal cells.

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References

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    1. Nucleic Acids Res. 1975 Jan;2(1):61-78 - PubMed
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    1. Nature. 1975 May 1;255(5503):33-7 - PubMed

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