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. 1992 Feb 20;355(6362):743-5.
doi: 10.1038/355743a0.

Renaturation of DNA catalysed by yeast DNA repair and recombination protein RAD10

P Sung  1 , L Prakash, S Prakash
Affiliations

Renaturation of DNA catalysed by yeast DNA repair and recombination protein RAD10

P Sung et al. Nature. .

Abstract

The RAD10 gene of Saccharomyces cerevisiae is required for the incision step of excision repair of ultraviolet-damaged DNA, and it functions in mitotic recombination. RAD10 has homology to the human excision repair gene ERCC-1. Here we describe the purification of the protein encoded by RAD10 and show that it is a DNA-binding protein with a strong preference for single-stranded DNA. We also show that RAD10 promotes the renaturation of complementary DNA strands.

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