doi: 10.1093/nar/20.2.315.
Poly(rA) binds poly(rG).poly(rC) to form a triple helix
Affiliations
- PMID: 1741257
- PMCID: PMC310372
- DOI: 10.1093/nar/20.2.315
Item in Clipboard
Poly(rA) binds poly(rG).poly(rC) to form a triple helix
Nucleic Acids Res.
.
Free PMC article
Abstract
Poly(rA) binds poly(rG).poly(rC) to form a triple helix. Evidence for this structure includes ultraviolet absorbance mixing curves and melting curves, and circular dichroism spectroscopy. The formation of the triple helix depends on the length of the poly(rC) strand. Triple helix forms when the average length is around 100 nucleotides but does not form when the average length is about 500 nucleotides.
Similar articles
-
The binding of DNA intercalating and non-intercalating compounds to A-form and protonated form of poly(rC).poly(rG): spectroscopic and viscometric study.Bioorg Med Chem. 2006 Feb 1;14(3):800-14. doi: 10.1016/j.bmc.2005.09.007. Epub 2005 Oct 3. Bioorg Med Chem. 2006. PMID: 16202606
-
Double-stranded RNA homopolymer poly(rC).poly(rG) for a new pH-sensitive drug carrier.Mol Pharm. 2008 Jan-Feb;5(1):162-4. doi: 10.1021/mp7001076. Epub 2007 Dec 28. Mol Pharm. 2008. PMID: 18161943
-
Triple helical polynucleotidic structures: an FTIR study of the C+ .G. Ctriplet.J Biomol Struct Dyn. 1992 Dec;10(3):577-88. doi: 10.1080/07391102.1992.10508669. J Biomol Struct Dyn. 1992. PMID: 1492925
-
Structural transitions in poly(A), poly(C), poly(U), and poly(G) and their possible biological roles.J Biomol Struct Dyn. 2019 Jul;37(11):2837-2866. doi: 10.1080/07391102.2018.1503972. Epub 2018 Nov 18. J Biomol Struct Dyn. 2019. PMID: 30052138 Review.
-
Interactions of oligopeptides with nucleic acids.CRC Crit Rev Biochem. 1981;10(3):213-58. doi: 10.3109/10409238109113600. CRC Crit Rev Biochem. 1981. PMID: 6260429 Review. No abstract available.
Cited by
-
Binding of oligonucleotides to a viral hairpin forming RNA triplexes with parallel G*G*C triplets.Nucleic Acids Res. 2002 Mar 15;30(6):1333-7. doi: 10.1093/nar/30.6.1333. Nucleic Acids Res. 2002. PMID: 11884630 Free PMC article.
-
Ligand-induced formation of nucleic acid triple helices.Proc Natl Acad Sci U S A. 1994 Sep 27;91(20):9332-6. doi: 10.1073/pnas.91.20.9332. Proc Natl Acad Sci U S A. 1994. PMID: 7524074 Free PMC article.
-
Protonated pyrimidine-purine-purine triplex.Nucleic Acids Res. 1993 Jan 11;21(1):105-11. doi: 10.1093/nar/21.1.105. Nucleic Acids Res. 1993. PMID: 8382787 Free PMC article.
-
A complex RNA motif defined by three discontinuous 5-nucleotide-long strands is essential for Flavivirus RNA replication.RNA. 2008 Sep;14(9):1791-813. doi: 10.1261/rna.993608. Epub 2008 Jul 30. RNA. 2008. PMID: 18669441 Free PMC article.
-
Exclusion of RNA strands from a purine motif triple helix.Nucleic Acids Res. 1994 Dec 11;22(24):5321-5. doi: 10.1093/nar/22.24.5321. Nucleic Acids Res. 1994. PMID: 7529405 Free PMC article.
References
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
