Case Reports
doi: 10.1097/DAD.0b013e31802e49a3.
A metastatic melanoma with an unusual immunophenotypic profile
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- PMID: 17414440
- DOI: 10.1097/DAD.0b013e31802e49a3
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Case Reports
A metastatic melanoma with an unusual immunophenotypic profile
Am J Dermatopathol.
2007 Apr.
Abstract
The most commonly used melanocytic markers are S100, HMB45, Melan-A, or MART-1 and tyrosinase. Melanoma with complete, concordant loss of these markers has not been reported. We report a case of metastatic melanoma with complete loss of staining for S100, HMB45, Melan-A, and tyrosinase. Interestingly, both the primary melanoma and its metastasis were strongly positive for CD99.
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