Waiting to inhale: HIF-1 modulates aerobic respiration
- PMID: 17418782
- DOI: 10.1016/j.cell.2007.03.031
Waiting to inhale: HIF-1 modulates aerobic respiration
Abstract
The hypoxia-inducible factor HIF-1 is known to promote anaerobic respiration during low oxygen conditions (hypoxia). In this issue, Fukuda et al. (2007) expand the range of HIF-1's functions by showing that it modulates aerobic respiration as well.
Comment on
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HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells.Cell. 2007 Apr 6;129(1):111-22. doi: 10.1016/j.cell.2007.01.047. Cell. 2007. PMID: 17418790
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