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Review
. 2007 Apr 6;129(1):33-6.
doi: 10.1016/j.cell.2007.03.019.

Development in motion: helper T cells at work

Steven L Reiner  1
Affiliations
Free article
Review

Development in motion: helper T cells at work

Steven L Reiner. Cell. .
Free article

Abstract

In mammals, helper T cells orchestrate defense against diverse pathogens. However, these warriors of the immune system can also result in self-inflicted injury culminating in autoimmune and allergic diseases. Recent findings--such as the discovery of the Th17 lineage--have revealed additional complexity in the fates chosen by helper T cells and have begun to reshape our view of how signaling and transcriptional networks generate appropriate and inappropriate immunity.

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