[Study of the symplast-forming activity of terpene and standard strains of Aujeszky's disease virus]

Abstract

Studied were the cellular changes and, more specifically, the production of symplasts as a particular form of manifesting the cytopathic effect of some strains of the Aujezsky's virus. Experiments with eight strains of the virus in tissue cultures confirmed the concept of a number of authors that in given tissue cultures virulent strains show a well pronounced trent toward the formation of symplasts containing numerous nuclei, while the latent strains stimulate the production of sporadic, rounded giant cells with a few nuclei in the aggregated cytoplasm. In the course of the investigations the primary cultures of rabbit kidney proved very suitable to demonstrate the presence of Aujeszky's disease and differentiate latent and virulent strains because of the cultures exceptional receptivity to the Aujeszky virus.