Myeloid bodies formation in triparanol treated cultured cells
- PMID: 174285
- DOI: 10.1007/BF02889378
Myeloid bodies formation in triparanol treated cultured cells
Abstract
Cultured cells (chicken embryo liver cells and rat embryo fibroblasts) were treated with triparanol (MER-29) for various lengths of time. Both types of cells have developed numerous membranous whorls-myeloid bodies in the cytoplasm. Various stages in myeloid bodies development are described. Acid phosphatase activity was cytochemically demonstrated within the myeloid bodies, indicating their lysosmal nature. This activity appeared only at a late stage of the myeloid bodies formation.
Similar articles
-
Effect of triparanol (mer 29) on rat liver lysosomes: cytochemical and biochemical study.Histochemie. 1973 Jul 19;36(1):5-14. doi: 10.1007/BF00310115. Histochemie. 1973. PMID: 4355421 No abstract available.
-
Formation of myeloid bodies in rat liver lysosomes after chloroquine administration.Exp Mol Pathol. 1968 Oct;9(2):212-29. doi: 10.1016/0014-4800(68)90037-3. Exp Mol Pathol. 1968. PMID: 4952073 No abstract available.
-
Giant dense bodies in fibroblasts cultured from beige mice with the Chédiak-Higashi syndrome.Am J Pathol. 1981 Dec;105(3):270-8. Am J Pathol. 1981. PMID: 6274200 Free PMC article.
-
Light-microscopic demonstration of drug-induced myelin bodies in the liver of rats.Experientia. 1974 Apr 15;30(4):385-6. doi: 10.1007/BF01921679. Experientia. 1974. PMID: 4366010 No abstract available.
-
[Drug-induced lipidosis: formation of myeloid bodies (author's transl)].Tanpakushitsu Kakusan Koso. 1974 Apr;19(4):275-93. Tanpakushitsu Kakusan Koso. 1974. PMID: 4369542 Review. Japanese. No abstract available.
Cited by
-
The subcellular distribution of small molecules: from pharmacokinetics to synthetic biology.Mol Pharm. 2011 Oct 3;8(5):1619-28. doi: 10.1021/mp200092v. Epub 2011 Aug 15. Mol Pharm. 2011. PMID: 21805990 Free PMC article. Review.
-
Pulmonary and generalized lysosomal storage induced by amphiphilic drugs.Environ Health Perspect. 1984 Apr;55:53-76. doi: 10.1289/ehp.845553. Environ Health Perspect. 1984. PMID: 6376111 Free PMC article. Review.
MeSH terms
Substances
LinkOut - more resources
Miscellaneous