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Review
. 2007 Apr;8(4):501-7.
doi: 10.2174/138945007780362782.

Endothelium as a therapeutic target in sepsis

William C Aird  1
Affiliations
Review

Endothelium as a therapeutic target in sepsis

William C Aird. Curr Drug Targets. 2007 Apr.

Abstract

The endothelium plays an important role in health and disease. Endothelial dysfunction contributes to sepsis pathophysiology. An important goal is to develop novel therapies that reverse endothelial dysfunction in sepsis. This review will consider the role of the endothelium in sepsis and will highlight its untapped therapeutic potential.

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