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Comparative Study
. 2007 Mar;32(2):299-307.
doi: 10.1007/s12038-007-0030-3.

Chondroprotective potential of root extracts of Withania somnifera in osteoarthritis

Venil N Sumantran  1 , Asavari Kulkarni, Sanjay Boddul, Trushna Chinchwade, Soumya J Koppikar, Abhay Harsulkar, Bhushan Patwardhan, Arvind Chopra, Ulhas V Wagh
Affiliations
Comparative Study

Chondroprotective potential of root extracts of Withania somnifera in osteoarthritis

Venil N Sumantran et al. J Biosci. 2007 Mar.

Abstract

This is the first report describing two novel chondroprotective activities of aqueous extracts of Withania somnifera root powder.First,these extracts had a statistically significant,short-term chondroprotective effect on damaged human osteoarthritic cartilage matrix in 50% of the patients tested. Second,these extracts caused a significant and reproducible inhibition of the gelatinase activity of collagenase type 2 enzyme in vitro.

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References

    1. Acta Biochim Pol. 2000;47(4):1081-91 - PubMed
    1. Osteoarthritis Cartilage. 2003 Jun;11(6):424-32 - PubMed
    1. Biochim Biophys Acta. 2000 Mar 16;1478(1):51-60 - PubMed
    1. Electrophoresis. 1998 Jun;19(8-9):1397-402 - PubMed
    1. J Bone Joint Surg Br. 1961 Nov;43-B:752-7 - PubMed

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