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. 2007 Apr;11(4):508-14.
doi: 10.1007/s11605-006-0031-9.

Intestinal perforations in Behçet's disease

Shao-Jiun Chou  1 , Victor Tze-Kai Chen, Hsiang-Chun Jan, Mary Ann Lou, Yi-Ming Liu
Affiliations

Intestinal perforations in Behçet's disease

Shao-Jiun Chou et al. J Gastrointest Surg. 2007 Apr.

Abstract

Behçet's disease accompanied by intestinal involvement is called intestinal Behçet's disease. The intestinal ulcers of Behçet's disease are usually multiple and scattered and tend to perforate easily, so that many patients require emergency operation. The aim of this study is to determine the extent of surgical resection necessary to prevent reperforation and to point out the findings of concurrent oral and genital ulcers and multiple intestinal perforations in all patients of our series. During a 25-year study period, information of 125 Behçet's disease cases was gathered. Among the 82 patients who were diagnosed with intestinal Behçet's disease, 22 cases had intestinal perforations needing emergency laparotomy. We investigated and analyzed these cases according to the patients' demographic characteristics, clinical presentations, laboratory data, and surgical outcome. There were 14 men and 8 women ranging from 22 to 65 years of age. Nine cases were diagnosed preoperatively, and the diagnoses were confirmed in all 22 cases during the surgical intervention. Surgical resection was performed in every patient, with right hemicolectomy and ileocecal resection in 11 cases, partial ileum resection in 8 cases with two reperforations, and ileocecal resection in 3 cases with one reperforation.

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Figures

Figure 1
Figure 1
Buccal ulcer.
Figure 2
Figure 2
Penile ulcer.
Figure 3
Figure 3
Nodular cutaneous lesion on the back.
Figure 4
Figure 4
Vasculitis characterized by lymphocytic and plasmacytic infiltration of perivascular tissue (hematoxylin and eosin; 10 × 40).
Figure 5
Figure 5
Surgical specimen of ileocecal region showing multiple penetrating ulcers.
Figure 6
Figure 6
Chronic inflammatory response and perivascular infiltration (hematoxylin and eosin; 10 × 10).
See this image and copyright information in PMC

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