Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2007 Apr;4(4):e117.
doi: 10.1371/journal.pmed.0040117.

Rotavirus infection: a systemic illness?

David C A Candy  1
Affiliations
Comment

Rotavirus infection: a systemic illness?

David C A Candy. PLoS Med. 2007 Apr.

Abstract

Candy discusses a new study inPLoS Medicine that challenges the view that in children with rotavirus diarrhea, the virus is confined to the upper small intestine.

PubMed Disclaimer

Conflict of interest statement

Competing Interests: The author has declared that no competing interests exist.

Figures

None
Electron micrograph showing a number of RNA rotavirus virions (which have a wheel-like appearance) and a number of unknown, 29 nm virion particles
See this image and copyright information in PMC

Comment on

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Bishop RF, Davidson GP, Holmes IH, Ruck BJ. Virus particles in epithelial cells of duodenal mucosa from children with acute non-bacterial gastroenteritis. Lancet. 1973;2:1281–1283. - PubMed
    1. Shornikova AV, Casas IA, Isolauri E, Mykkanen H, Vesikari T. Lactobacillus reuteri as a therapeutic agent in acute diarrhea in young children. J Pediatr Gastroenterol Nutr. 1997;24:399–404. - PubMed
    1. Osborne MP, Haddon SJ, Spencer AJ, Collins J, Starkey WG, et al. An electron microscopic investigation of time-related changes in the intestine of neonatal mice infected with murine rotavirus. J Pediatr Gastroenterol Nutr. 1988;7:236–248. - PubMed
    1. Lynch M, Lee B, Azimi P, Gentsch J, Glaser C, et al. Rotavirus and central nervous system symptoms: Cause or contaminant? Case reports and review. Clin Infect Dis. 2001;33:932–938. - PubMed
    1. Blutt SE, Matson DO, Crawford SE, Staat MA, Azimi P, et al. Rotavirus antigenemia in children is associated with viremia. PLoS Med. 2007;4:e121. doi: 10.1371/journal.pmed.0040121. - DOI - PMC - PubMed