Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2007 Apr 20;316(5823):370.
doi: 10.1126/science.316.5823.370a.

Comment on "Ongoing adaptive evolution of ASPM, a brain size determinant in Homo sapiens"

Fuli Yu  1 , R Sean Hill, Stephen F Schaffner, Pardis C Sabeti, Eric T Wang, Andre A Mignault, Russell J Ferland, Robert K Moyzis, Christopher A Walsh, David Reich
Affiliations
Comment

Comment on "Ongoing adaptive evolution of ASPM, a brain size determinant in Homo sapiens"

Fuli Yu et al. Science. .

Abstract

Mekel-Bobrov et al. (Reports, 9 September 2005, p. 1720) suggested that ASPM, a gene associated with microcephaly, underwent natural selection within the last 500 to 14,100 years. Their analyses based on comparison with computer simulations indicated that ASPM had an unusual pattern of variation. However, when we compare ASPM empirically to a large number of other loci, its variation is not unusual and does not support selection.

PubMed Disclaimer

Comment on

Publication types

LinkOut - more resources