Zfx: at the crossroads of survival and self-renewal
- PMID: 17448983
- DOI: 10.1016/j.cell.2007.04.002
Zfx: at the crossroads of survival and self-renewal
Abstract
As the molecular mechanisms that govern stem cell fate are beginning to be unraveled, Galan-Caridad et al. (2007) report in this issue of Cell a common role for the transcription factor Zfx in the self-renewal/maintenance of both embryonic stem cells and hematopoietic stem cells. Their work suggests that a regulator of self-renewal can be shared between two different cell types.
Comment on
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Zfx controls the self-renewal of embryonic and hematopoietic stem cells.Cell. 2007 Apr 20;129(2):345-57. doi: 10.1016/j.cell.2007.03.014. Cell. 2007. PMID: 17448993 Free PMC article.
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