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. 2007 May;150(5):474-8.
doi: 10.1016/j.jpeds.2006.12.045.

Delayed developmental language milestones in children with Duchenne's muscular dystrophy

Shana E Cyrulnik  1 , Robert J Fee, Darryl C De Vivo, Edward Goldstein, Veronica J Hinton
Affiliations

Delayed developmental language milestones in children with Duchenne's muscular dystrophy

Shana E Cyrulnik et al. J Pediatr. 2007 May.

Abstract

Objectives: To document the attainment of developmental milestones in children with Duchenne's muscular dystrophy (DMD) and to determine whether early delays are associated with later performance on measures of cognition.

Study design: Retrospective parental report was utilized to document the acquisition of 10 common developmental milestones in children with DMD (n = 130) and their unaffected siblings (n = 59). Children completed tests of cognitive functioning.

Results: Parents rated children with DMD as delayed on achieving both language and motor milestones more frequently than their unaffected siblings. Furthermore, those children with DMD who were rated as late talkers or late walkers performed more poorly on tests of cognitive function than their on-time peers.

Conclusions: In addition to the commonly reported delays in motor milestones, the current study documents delays in the acquisition of language milestones as well. These early delays are associated with significant impairments in later cognitive functioning.

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Comment in

  • Muscle memory.
    Iannaccone ST. Iannaccone ST. J Pediatr. 2007 May;150(5):456-7. doi: 10.1016/j.jpeds.2007.02.056. J Pediatr. 2007. PMID: 17452213 No abstract available.

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