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. 2007 Jul;51(7):2587-90.
doi: 10.1128/AAC.00452-07. Epub 2007 Apr 23.

In vitro susceptibilities of 217 clinical isolates of zygomycetes to conventional and new antifungal agents

Nikolaos G Almyroudis  1 , Deanna A Sutton, Annette W Fothergill, Michael G Rinaldi, Shimon Kusne
Affiliations

In vitro susceptibilities of 217 clinical isolates of zygomycetes to conventional and new antifungal agents

Nikolaos G Almyroudis et al. Antimicrob Agents Chemother. 2007 Jul.

Abstract

We evaluated the in vitro susceptibilities of 217 zygomycetes to amphotericin B, ketoconazole, fluconazole, itraconazole, voriconazole, posaconazole, caspofungin, and flucytosine. The significant in vitro activity of posaconazole against several species appears to support its reported clinical efficacy. Decreased susceptibility to amphotericin B was noted with Cunninghamella bertholletiae.

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