[The heart, the elderly, and diabetes mellitus. Epidemiologic study of 333 ambulatory clinical cases]

Abstract

The paper proposes a new classification to describe the normal senile heart and its pathological forms: "small aortic heart" (nonhypertrophic-dilatative myocardiopathy and its ischemic form) and "large aortic heart" (hypertrophic-dilatative myocardiopathy and its ischemic form). The statistical distribution of 241 elderly patients with diabetes mellitus using this classification was compared to a control group of 92 elderly non-diabetic subjects. The results reveal the significant epidemiological incidence of ischemic cardiopathy with small aortic heart in diabetic patients compared to the control group in which more ischemic hypertrophic-dilatative cardiopathies were present. This observation supports the hypothesis that senile diabetic cardiopathy begins with a metabolic block with reduced contractile energy, and the overlying important ischemic component leads to the development of the small-size clinical phenotype.