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. 2007 May;8(5):1723-9.
doi: 10.1021/bm070082k. Epub 2007 Apr 26.

Self-assembly of conjugated polymers and ds-oligonucleotides directed fractal-like aggregates

Haiyang Gan  1 , Yuliang Li, Huibiao Liu, Shu Wang, Cuihong Li, Mingjian Yuan, Xiaofeng Liu, Chunru Wang, Lei Jiang, Daoben Zhu
Affiliations

Self-assembly of conjugated polymers and ds-oligonucleotides directed fractal-like aggregates

Haiyang Gan et al. Biomacromolecules. 2007 May.

Abstract

Highly ordered nanostructures between conjugated polymers and ds-oligonucleotides have been first fabricated by simply controlling the self-assembly processes, which shows a novel concept for fabricating fractal-like structures. The formation of polymer/DNA fractal-like aggregates is a diffusion-limited aggregation (DLA) process. The fractal dimension is independent of the polymer/DNA concentration but only related to the polymer/DNA charge ratio. More interestingly, the different fluorescent resonance energy transfer (FRET) behavior between the polymer and the DNA can be used to distinguish dsDNA from ssDNA.

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