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. 2007 May 24;9(11):2063-6.
doi: 10.1021/ol070506n. Epub 2007 Apr 26.

Highly stereoselective prins cyclization of (Z)- and (E)-gamma-brominated homoallylic alcohols to 2,4,5,6-tetrasubstituted tetrahydropyrans

Feng Liu  1 , Teck-Peng Loh
Affiliations

Highly stereoselective prins cyclization of (Z)- and (E)-gamma-brominated homoallylic alcohols to 2,4,5,6-tetrasubstituted tetrahydropyrans

Feng Liu et al. Org Lett. .

Abstract

An efficient method has been developed to construct 2,6-cis-4,5-dibromo-tetrasubstituted tetrahydropyran (THP) rings with well-controlled stereochemistry in moderate to high yields.

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