Antigen to the node: B cells go native
- PMID: 17459806
- DOI: 10.1016/j.immuni.2007.04.002
Antigen to the node: B cells go native
Abstract
The participation of B and T cells in an immune response requires their separate activation by different forms of the target antigen. In this issue of Immunity, Pape et al. (2007) describe antigen entry into the B cell areas in the lymph node without degradation or cellular assistance.
Comment on
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The humoral immune response is initiated in lymph nodes by B cells that acquire soluble antigen directly in the follicles.Immunity. 2007 Apr;26(4):491-502. doi: 10.1016/j.immuni.2007.02.011. Epub 2007 Mar 22. Immunity. 2007. PMID: 17379546
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