Nucleotide sequence diversity of the bexA gene in serotypeable Haemophilus influenzae strains recovered from invasive disease patients in Canada
- PMID: 17460059
- PMCID: PMC1933025
- DOI: 10.1128/JCM.00612-07
Nucleotide sequence diversity of the bexA gene in serotypeable Haemophilus influenzae strains recovered from invasive disease patients in Canada
Abstract
The bexA genes of 36 Haemophilus influenzae isolates were sequenced to reveal their nucleotide sequence diversity, which divided them into two groups, similar to clonal divisions I and II. This sequence diversity may lead to false-negative PCR results for H. influenzae infections if bexA is the chosen gene target.
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- Corless, C. E., M. Guiver, R. Borrow, V. Edward-Jones, A. J. Fox, and E. B. Kaczmarsk. 2001. Simultaneous detection of Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae in suspected cases of meningitis and septicemia using real-time PCR. J. Clin. Microbiol. 39:1553-1558. - PMC - PubMed
-
- Dworkin, M. S., L. Park, and S. M. Borchardt. 2007. The changing epidemiology of invasive Haemophilus influenzae disease, especially in persons ≥65 years old. Clin. Infect. Dis. 44:810-816. - PubMed
-
- Frosch, M., and A. Muller. 1993. Phospholipid substitution of capsular polysaccharides and mechanisms of capsule formation in Neisseria meningitidis. Mol. Microbiol. 8:483-493. - PubMed
-
- Kilian, M. 2003. Haemophilus, p. 623-635. In P. R. Murray, E. J. Baron, J. H. Jorgensen, M. A. Pfaller, and R. H. Yolken (ed.), Manual of clinical microbiology, 8th ed. ASM Press, Washington, DC.
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